Riveras E, Alvarez JM, Vidal EA, Oses C, Vega A, Gutierrez RA (2015) Ca2+ is a second messenger in the nitrate signaling pathway of Arabidopsis thaliana. Plant Physiol 169: 1397–1404

Vega A, Canessa P, Hoppe G, Retamal I, Moyano TC, Canales J, Gutiérrez RA, Rubilar J (2015) Transcriptome analysis reveals regulatory networks underlying differential susceptibility to Botrytis cinerea in response to nitrogen availability in Solanum lycopersicum. Front Plant Sci 6: 911

Vidal EA, Alvarez JM, Moyano TC, Gutierrez RA (2015) Transcriptional networks in the nitrate response of Arabidopsis thaliana. Curr Opin Plant Biol 27: 125–132

Acuna M, Martinez P, Moraga C, He X, Moraga M, Hunter B, Nuernberg P, Gutiérrez RA, Gonzalez M, Schuchman EH, Luis Santos J, Miquel JF, Mabe P, Zanlungo S (2015). Epidemiological, clinical and biochemical characterization of the p.(Ala359Asp) SMPD1 variant causing Niemann-Pick disease type B. Eur J Hum Genet. PubMed

Moyano TC, Vidal EA, Contreras-Lopez O, Gutiérrez RA (2015). Constructing simple biological networks for understanding complex high-throughput data in plants. Methods Mol Biol1284, 503-26. PubMed

Vidal EA, Moyano TC, Canales J, Gutiérrez RA (2014). Nitrogen control of developmental phase transitions in Arabidopsis thaliana. J Exp Bot. PubMed

Alvarez JM, Riveras E, Vidal EA, Gras DE, Contreras-Lopez O, Tamayo KP, Aceituno F, Gomez I, Ruffel S, Lejay L, Jordana X, Gutiérrez RA (2014). Systems approach identifies TGA1 and TGA4 transcription factors as important regulatory components of the nitrate response of Arabidopsis thaliana roots. Plant J. PubMed

Vidal EA, Alvarez JM, Gutiérrez RA (2014). Nitrate regulation of AFB3 and NAC4 gene expression in Arabidopsis roots depends on NRT1.1 nitrate transport function. Plant Signal Behav9. PubMed

Canales J, Moyano TC, Villarroel E, Gutiérrez RA (2014). Systems analysis of transcriptome data provides new hypotheses about Arabidopsis root response to nitrate treatments. Front Plant Sci5, 22. PubMedDownload

Federici F, Rudge TJ, Pollak B, Haseloff J, Gutiérrez RA (2013). Synthetic Biology: opportunities for Chilean bioindustry and education. Biol Res46, 383-93. PubMed

Vidal EA, Moyano TC, Riveras E, Contreras-Lopez O, Gutiérrez RA (2013). Systems approaches map regulatory networks downstream of the auxin receptor AFB3 in the nitrate response of Arabidopsis thaliana roots. Proc Natl Acad Sci U S A110, 12840-5. PubMedDownload

Zuniga A, Poupin MJ, Donoso R, Ledger T, Guiliani N, Gutiérrez RA, Gonzalez B (2013). Quorum sensing and indole-3-acetic acid degradation play a role in colonization and plant growth promotion of Arabidopsis thaliana by Burkholderia phytofirmans PsJN. Mol Plant Microbe Interact 26, 546-53. PubMed Download

Puelma T, Gutiérrez RA, Soto A (2012). Discriminative local subspaces in gene expression data for effective gene function prediction. Bioinformatics 28, 2256-64. PubMed Download

 Gutiérrez RA (2012). Systems biology for enhanced plant nitrogen nutrition. Science 336, 1673-5. PubMed[Reprint]

Alvarez JM, Vidal EA, Gutiérrez RA (2012). Integration of local and systemic signaling pathways for plant N responses. Curr Opin Plant Biol 15, 185-91. PubMed Download

Fuentes D, Meneses M, Nunes-Nesi A, Araujo WL, Tapia R, Gomez I, Holuigue L, Gutiérrez RA, Fernie AR, Jordana X (2011). A deficiency in the flavoprotein of Arabidopsis mitochondrial complex II results in elevated photosynthesis and better growth in nitrogen-limiting conditions. Plant Physiol 157, 1114-27. PubMed Download

Vega A, Gutiérrez RA, Pena-Neira A, Cramer GR, Arce-Johnson P (2011). Compatible GLRaV-3 viral infections affect berry ripening decreasing sugar accumulation and anthocyanin biosynthesis in Vitis vinifera. Plant Mol Biol77, 261-74. PubMed Download

Krouk G, Ruffel S, Gutiérrez RA, Gojon A, Crawford NM, Coruzzi GM, Lacombe B (2011). A framework integrating plant growth with hormones and nutrients. Trends Plant Sci 16, 178-82. PubMed Download

Kraiser T, Gras DE, Gutierrez AG, Gonzalez B, Gutiérrez RA (2011). A holistic view of nitrogen acquisition in plants. J Exp Bot 62, 1455-66. PubMed Download

International Arabidopsis Informatics Consortium (2010). An international bioinformatics infrastructure to underpin the Arabidopsis community. Plant Cell 22, 2530-6. PubMed Download

Vidal EA, Araus V, Lu C, Parry G, Green PJ, Coruzzi GM, Gutiérrez RA (2010). Nitrate-responsive miR393/AFB3 regulatory module controls root system architecture in Arabidopsis thaliana. Proc Natl Acad Sci U S A . PubMedDownload 

McClung CR, Gutiérrez RA (2010). Network news: prime time for systems biology of the plant circadian clock.Curr Opin Genet Dev . PubMed Download

Vidal EA, Tamayo KP, Gutiérrez RA (2010). Gene networks for nitrogen sensing, signaling, and response in Arabidopsis thaliana. Wiley Interdiscip Rev Syst Biol Med 2, 683-93. PubMed Download

Katari MS, Nowicki SD, Aceituno FF, Nero D, Kelfer J, Thompson LP, Cabello JM, Davidson RS, Goldberg AP, Shasha DE, Coruzzi GM, Gutiérrez RA (2010). VirtualPlant: a software platform to support systems biology research.Plant Physiol 152, 500-15. PubMed Download

Das M, Reichman JR, Haberer G, Welzl G, Aceituno FF, Mader MT, Watrud LS, Pfleeger TG, Gutiérrez RA, Schaffner AR, Olszyk DM (2010). A composite transcriptional signature differentiates responses towards closely related herbicides in Arabidopsis thaliana and Brassica napus. Plant Mol Biol 72, 545-56. PubMed Download

Krouk G , Tranchina D , Lejay L , Cruikshank AA , Shasha D , Coruzzi GM , Gutiérrez RA (2009). A systems approach uncovers restrictions for signal interactions regulating genome-wide responses to nutritional cues in Arabidopsis. PLoS Comput Biol 5, e1000326. PubMed Download

Reforgiato D, Gutiérrez RA, Shasha D (2008). GraphClust: A Method for Clustering Database of Graphs. J Information & Knowledge Management. 7, 231-241.

Bender J, Benfey P, Bergmann D, Borevitz J, Coruzzi G, Dangl J, Dean C, Ecker J, Estelle M, Glazebrook J, Grant S, Guerinot ML, Gutierrez R, Long J, Nordborg M, Poethig S, Raikhel N, Schmitt J, Schnittger A, Vidal M (2008). 2020 vision for biology: the role of plants in addressing grand challenges in biology. Mol Plant 1, 561-3. PubMed

Aceituno FF, Moseyko N, Rhee SY, Gutiérrez RA (2008). The rules of gene expression in plants: Organ identity and gene body methylation are key factors for regulation of gene expression in Arabidopsis thaliana. BMC Genomics 9, 438. PubMed Download  [Supplemental Material] 

Holuigue L, Vielle-Calzada JP, Gutiérrez RA (2008). Crops in all shapes and sizes. Genome Biol 9, 319. PubMed

Vidal EA, Gutiérrez RA (2008). A systems view of nitrogen nutrient and metabolite responses in Arabidopsis.Curr Opin Plant Biol 11, 521-9. PubMed Download

Thum KE, Shin MJ, Gutiérrez RA, Mukherjee I, Katari MS, Nero D, Shasha D, Coruzzi GM (2008). An integrated genetic, genomic and systems approach defines gene networks regulated by the interaction of light and carbon signaling pathways in Arabidopsis. BMC Syst Biol 2, 31. PubMed Download 

Gutiérrez RA , Stokes TL , Thum K , Xu X , Obertello M , Katari MS , Tanurdzic M , Dean A , Nero DC , McClung CR , Coruzzi GM (2008). Systems approach identifies an organic nitrogen-responsive gene network that is regulated by the master clock control gene CCA1. Proc Natl Acad Sci U S A 105 , 4939-44. PubMed Download

Gifford ML , Dean A , Gutiérrez RA , Coruzzi GM , Birnbaum KD (2008). Cell-specific nitrogen responses mediate developmental plasticity. Proc Natl Acad Sci U S A 105 , 803-8. PubMed Download 

Gutiérrez RA, Gifford ML, Poultney C, Wang R, Shasha DE, Coruzzi GM, Crawford NM (2007). Insights into the genomic nitrate response using genetics and the Sungear Software System. J Exp Bot 58, 2359-67. PubMedDownload

Gutiérrez RA, Lejay LV, Dean A, Chiaromonte F, Shasha DE, Coruzzi GM (2007). Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis. Genome Biol8, R7. PubMed Download

Poultney CS, Gutiérrez RA, Katari MS, Gifford ML, Paley WB, Coruzzi GM, Shasha DE (2007). Sungear: interactive visualization and functional analysis of genomic datasets. Bioinformatics 23, 259-61. PubMed Download

Li C, Potuschak T, Colon-Carmona A, Gutiérrez RA, Doerner P (2005). Arabidopsis TCP20 links regulation of growth and cell division control pathways. Proc Natl Acad Sci U S A 102, 12978-83. PubMed Download

Lidder P*, Gutiérrez RA*, Salome PA, McClung CR, Green PJ (2005). Circadian control of messenger RNA stability. Association with a sequence-specific messenger RNA decay pathway. *Both authors contributed equally. Plant Physiol 138, 2374-85. PubMed Download

Gutiérrez RA, Shasha DE, Coruzzi GM (2005). Systems biology for the virtual plant. Plant Physiol 138, 550-4.PubMed Download

Wang R, Tischner R, Gutiérrez RA, Hoffman M, Xing X, Chen M, Coruzzi G, Crawford NM (2004). Genomic analysis of the nitrate response using a nitrate reductase-null mutant of Arabidopsis. Plant Physiol 136, 2512-22.PubMed Download

Gutiérrez RA*, Larson MD, Wilkerson C (2004). The plant-specific database. Classification of Arabidopsis proteins based on their phylogenetic profile. *Corresponding author. Plant Physiol 135, 1888-92. PubMed Download

Gutiérrez RA*, Green PJ, Keegstra K, Ohlrogge JB (2004). Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms? *Corresponding author. Genome Biol 5, R53.PubMed Download 

Gutiérrez RA, Ewing RM, Cherry JM, Green PJ (2002). Identification of unstable transcripts in Arabidopsis by cDNA microarray analysis: rapid decay is associated with a group of touch- and specific clock-controlled genes.Proc Natl Acad Sci U S A 99, 11513-8. PubMed Download

Ghosh D, Sawicki M, Lala P, Erman M, Pangborn W, Eyzaguirre J, Gutierrez RA, Jornvall H, Thiel DJ (2001). Multiple conformations of catalytic serine and histidine in acetylxylan esterase at 0.90 A. J Biol Chem 276, 11159-66.PubMed Download

Gutiérrez RA, MacIntosh GC, Green PJ (1999). Current perspectives on mRNA stability in plants: multiple levels and mechanisms of control. Trends Plant Sci 4, 429-438. PubMed Download

Ghosh D, Erman M, Sawicki M, Lala P, Weeks DR, Li N, Pangborn W, Thiel DJ, Jornvall H, Gutierrez RA, Eyzaguirre J (1999). Determination of a protein structure by iodination: the structure of iodinated acetylxylan esterase. Acta Crystallogr D Biol Crystallogr 55 ( Pt 4), 779-84. PubMed Download

Gutierrez R, Cederlund E, Hjelmqvist L, Peirano A, Herrera F, Ghosh D, Duax W, Jornvall H, Eyzaguirre J (1998). Acetyl xylan esterase II from Penicillium purpurogenum is similar to an esterase from Trichoderma reesei but lacks a cellulose binding domain. FEBS Lett 423, 35-8. PubMed Download

Egana L, Gutierrez R, Caputo V, Peirano A, Steiner J, Eyzaguirre J (1996). Purification and characterization of two acetyl xylan esterases from Penicillium purpurogenum. Biotechnol Appl Biochem 24 ( Pt 1), 33-9. PubMed

Pangborn W, Erman M, Li N, Burkhart BM, Pletnev VZ, Duax WL, Gutierrez R, Peirano A, Eyzaguirre J, Thiel DJ, Ghosh D (1996). Characterization of crystals of Penicillium purpurogenum acetyl xylan esterase from high-resolution x-ray diffraction. Proteins 24, 523-4. PubMed Download